“This is the first study with the cytokinins to show such improvement in almost all categories by both the investigator and subject assessments. The statistical significance in these changes is also quite impressive. The barrier effects on decreasing TEWL and increasing skin hydration are also very good. There are NO safety issues – no increase in acne – actually a decrease in overall acne and inflammatory lesions. The anti-inflammatory effects are noticeable. I particularly like the analysis separating the effects on erythema in those subjects who had pre-existing erythema vs those without erythema. This is very exciting – and would anticipate these improvements to increase at subsequent weeks!”