PyratineXR® is a medically proven treatment for rosacea and is the only known rosacea treatment that effectively helps eliminate the three key symptoms of this most troubling skin disease: facial redness, acne lesions and spider veins. Unlike other oral and topical rosacea treatments, PyratineXR®can be used continuously long term, an important benefit due to rosacea’s chronic incurable nature.

PyratineXR® is a powerful anti-inflammatory and is ideal for highly sensitive and irritated skin. The active ingredient in PyratineXR® is derived naturally from plants and is in your own body’s DNA. PyratineXR® nourishes the skin and helps restore the skin barrier function. PyratineXR® is not an acid, contains no harsh or irritating chemicals and soothes sensitive skin naturally.

PyratineXR® is a powerful antioxidant that helps smooth aging and sun-damaged skin, and reduces fine lines, wrinkles, and mottled hyperpigmentation. In clinical controlled studies designed using strict FDA protocols, PyratineXR®dramatically improved skin texture in just days and was shown to be more effective than Renova®, the only FDA approved (prescription) anti-aging product.

PyratineXR® is perhaps nature’s most powerful known moisturizer, significantly reducing water loss to the skin. PyratineXR® is highly effective in eliminating dry, patchy skin often associated with skin conditions like eczema, rosacea and atopic dermatitis. Controlled clinical trials demonstrated PyratineXR®’s ability to help repair the skin barrier function, dramatically increasing the amount of moisture retained in the skin.




"I’m amazed! I had a sample bottle of PyratineXR that I started using for redness around my eyes. Holy wrinkle destroyer! The crow’s nests I’ve had forever disappeared along with the red."

− J.B., Consumer

"I am 71 years old and have been using PyratineXR Lotion every morning for years. Not only did it help my rosacea, but it also helped minimize my pores. My skin look amazing. You would never think that I am 71 by looking at me!"

− L.K., Consumer

"Pyratine has been a complete miracle for me. I suffer with severe rosacea that had actually become debilitating. It was actually painful. I had to use ice packs at night to try to cool it down only a little bit. I used prescriptions…everything out there..with no relief, often times making it even worse. I stumbled upon Pyratine in a desperate internet search for help. I figured, why not? I’d tried it all, what’s one more thing? It has turned out to be a miracle for me. I had to stick with it though, as improvement took several good weeks. Once it did though, I have my life back!! Most days, you would not know I had rosacea, truly. My skin is amazing now. I can’t thank you guys enough for this miracle. I have corresponded with Frank personally from the company in times of despair, and he was so encouraging to me to stick with it. I’m so glad I am, and blessed to have found this product. Thank you Pyratine!! Guys, please don’t give up hope…give it a try!"

− Lori Matlak, Consumer

"I have found the Pyratine product to be the best product for my skin health. It’s absolutely the best item my dermatologist has recommended to me not only to calm my rosacea but also to improve my overall appearance. It’s a wonderful, wonderful, wonderful product! I recommend anyone with sensitive skin or rosacea to use it. I would actually also recommend it to folks without problem skin because the benefit it provides with also improving the skin and minimizing the wrinkles. It’s done wonders on my 60 year old skin."

− D.B., Consumer

"I have used this for only 2 weeks and I’m so happy with the results. I had markedly reduced redness after 2 days. It continues to diminish. I am so happy with this product. I have, in the last 12 years, tried everything and nothing really worked. This was like a miracle the first week. Redness diminishes immediately upon application. I do have to use it twice daily. It does work well under makeup."

− B.O. Borders, Consumer

"I’ve been using PyratineXR lotion for nine weeks. I apply it morning and right before bed. I noticed a subtle difference within two weeks, by the 6-8 week period the difference was remarkable. Fine blood vessels have disappeared. Redness has faded around my nose, cheeks and chin. Even the papules from my rosacea have shrunk as have my skin pores. This has really worked for me and I’m ordering my second tube. The 2oz size lasted about 2 1/2 months used twice daily. Frankly, I’m amazed that a product that has worked this well is OTC. I am so happy with the results. My 50 year old skin now looks as young as a 30 something. No kidding."

− R.B., Consumer

"This is the first review I have ever written for a product but it works so well, I feel I should. I have rosacea and have tried many things and nothing has worked as well as this product. I am not as consistent as I should be and still see very good results. . . No postules at all and only mild redness now. I happened to put this on my nose and found that it is also an amazing pore minimizer. . . Will continue to buy this product.”"

− Deborah L. Rasmussen, Consumer


PyratineXR® is specifically formulated for people with sensitive or irritated skin and effectively treats conditions such as eczema, rosacea and atopic dermatitis. Utilizing the power of advanced cytokinin technology, PyratineXR® reduces inflammation, restores essential moisture to the skin and improves the skin barrier function.

Cytokinins slow the aging process in plants and have been clinically proven to increase the life span of human cells and minimize free radicals, dramatically slowing the aging process and reducing fine lines, wrinkles, mottled hyperpigmentation and skin roughness.

Limiting the number of facial skin care products is key for individuals with sensitive or irritated skin. Moisturizers, anti-aging serums and anti-inflammatory creams typically contain dozens of harsh chemicals along with their active ingredients. The more products applied to the skin, the greater the risk of irritation. PyratineXR® is a multi-functional product—a moisturizer, anti-inflammatory agent and anti-aging product, all in one. It is truly the skin care line to end all lines.