The Sensitive Skin Solution

Soothe Irritated Skin

Clarify, brighten, smooth skin texture, diminish redness and increase moisture content, Pyratine® improves overall complexion.

Plant Derived

Pyratine® uses an advanced cytokinin technology derived from plants giving you the best mother earth has to offer, in its purest form.

Clinically Tested

Safety is our #1 concern at Pyratine® – we test all of our products with the same standards as new drugs submitted to the FDA. You can rest easy knowing you are in good hands. 

The PyratineXR® Difference


Improvement - Fine Wrinkles22%
Improvement - Hyperpigmentation31%
Improvement - Roughness86%
Improvement - Skin Overall24%

PyratineXR® – The Only Crème You Need

PyratineXR® has been clinically proven to improve skin barrier function and moisture retention with no clinical signs or symptoms of irritation.

All Pyratine® products are non-prescription developed using pharmaceutical grade standards.
Every compound in Pyratine’s products is tested as if it were being submitted as a new drug to the FDA — a standard that most traditional treatments do not meet.

We are so confident in our sensitive skin treatment that we back Pyratine® with a 100% satisfaction guarantee – no restocking fees, no hidden costs. You just need to pay for shipping and we will take the product back.

Introducing The PyratineXR® System

PyratineXR® Facial Cleanser

PyratineXR® Crème

PyratineXR® Crème

PyratineXR® Intensive
Anti-Redness Ointment

See if PyratineXR® is Right For You

What People Say About PyratineXR®

Pyratine has been a complete miracle for me. I suffer with severe rosacea that had actually become debilitating. It was actually painful. I had to use ice packs at night to try to cool it down only a little bit. I used prescriptions…everything out there..with no relief, often times making it even worse. I stumbled upon Pyratine in a desperate internet search for help. I figured, why not? I’d tried it all, what’s one more thing? It has turned out to be a miracle for me. I had to stick with it though, as improvement took several good weeks. Once it did though, I have my life back!! Most days, you would not know I had rosacea, truly. My skin is amazing now. I can’t thank you guys enough for this miracle. I have corresponded with Frank personally from the company in times of despair, and he was so encouraging to me to stick with it. I’m so glad I am, and blessed to have found this product. Thank you Pyratine!! Guys, please don’t give up hope…give it a try!

Lori Matlak Customer

I have used this for only 2 weeks and I’m so happy with the results. I had markedly reduced redness after 2 days. It continues to diminish. I am so happy with this product. I have, in the last 12 years, tried everything and nothing really worked. This was like a miracle the first week. Redness diminishes immediately upon application. I do have to use it twice daily. It does work well under makeup.

B.O. Borders Customer

I’ve been using PyratineXR lotion for nine weeks. I apply it morning and right before bed. I noticed a subtle difference within two weeks, by the 6-8 week period the difference was remarkable. Fine blood vessels have disappeared. Redness has faded around my nose, cheeks and chin. Even the papules from my rosacea have shrunk as have my skin pores. This has really worked for me and I’m ordering my second tube. The 2oz size lasted about 2 1/2 months used twice daily. Frankly, I’m amazed that a product that has worked this well is OTC. I am so happy with the results. My 50 year old skin now looks as young as a 30 something. No kidding.

R.B. Customer

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